Learn more about Bridelia uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Bridelia. Asas, Assas, Bridelia cathartica, Bridelia ferruginea , Bridelia grandis, Bridelia micrantha, Bridelia. In present study we explore dose dependent effects of Bridelia ferruginea on hematological parameters. The hematological responses of albino. A review of Bridelia ferruginea, Combretum glutinosum and Mitragina inermis plants used in zootherapeutic remedies in West Africa: historical.

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Conclusion The relative safety of the aqueous stem bark extract of Bridelia ferruginea as obtained in the present study is comparable to the report of Bakoma et al. Since this is a non-significant increase in organ ferrugine, by extrapolation and implication, the results may be an indication of the low toxicity and relative safety of the extract.

In this study we have used cellular models of CNS inflammation to show that a stem bark extract of B.

Preparations fferruginea the Extracts. The membranes were blocked for 2 hours at room temperature using Rotiblock Roth, Karlsruhe, Germany or nonfat dry milk blotting grade blocker Biorad, USA and incubated overnight with primary antibodies.

To investigate whether BFE interferes with these mediators, experiments were carried out to determine its effects on their production in LPS-stimulated BV-2 microglia. Anaemia and red blood cell transfusion in the critically ill patient.

Equal protein loading and transfer were assessed by subjection of each sample to a western blot for actin rabbit antiactin IgG, diluted 1: It is usually a gnarled shrub, which sometimes reach the size of a tree when grown in a suitable environment.

The animals were sacrificed after 60 days. Open in a separate window. High neutrophil counts can be the result of many factors that include bacterial infection, acute inflammation, stress response effect from some drugs and splenectomy, among others Owoseni et al.


Bridelia ferruginea

I of drugs Rang et al. Results and Discussion 3. Confluent monolayers were passaged routinely by trypsinisation. At the end of each experiment, cells were washed with phosphate-buffered saline PBS and lysed in 1. Instances of adulteration, inappropriate formulations or lack of understanding of drugs and plant interactions or their uses leading to adverse reactions, sometimes life-threatening or lethal to patients, have been reported Ernst, Iwu asserted that the plant has molluscidal activities, while Adeoye et al reported that the bark extract of the plant has antimicrobial activities against some micro-organisms known to cause enteric and secondary upper respiratory tract infection.

At the end of the stimulation period, cells were washed with phosphate-buffered saline PBS and lysed with commercially available lysis buffer New England Biolabs, UK.

West African Plants – A Photo Guide – Bridelia ferruginea Benth.

The acute lethal effect of the aqueous stem bark extract of Bridelia ferruginea on rats produced no death brideliia 24 hours of treatment either via oral or intraperitoneal routes. However, the present study revealed the potential of this extract to cause lipid peroxidation and subsequent damage of sperm quality.

An extinction coefficient at nm hydrogen peroxide of Bgidelia a substantial number of scientific research papers have revealed the therapeutic activities of many African plants, there is paucity of data on the toxicity of these plant materials Abalaka et al. Topical anti-inflammatory, antiarthritic, antipyretic, and analgesic properties of the plant were also reported by us [ 6 ].

A cell viability assay carried out at the same time revealed that BFE did not affect viability of BV-2 microglia at concentrations which produced reductions in PGE 2nitrite and cytokines produced from the cells data not shown.


The serum ALP levels are also related to the status and function of hepatic cells and according to the literature, an increase in serum ALP may occur as a result of increased synthesis, in the presence of increasing biliary pressure.

Evidence-Based Complementary and Alternative Medicine

The decrease in WBC shown in Table ferrugiinea in the test groups compared to the control may imply that the aqueous stem bark extract of Bridelia ferruginea has the ability to cause immunosuppression. Histological changes in the kidney, brain, heart and liver of the animals were also examined at the end of administration of the extract. Please review our privacy policy. The medium was mixed gently for even distribution of the inoculums within the media and allowed to solidify at room temperature 25 0 c.

Ten microliters of eosin and nigrosin were mixed with about 40 microliters of sperm suspension.

An improved Neubauer ruled chamber was filled with the well-mixed diluted semen using a Pasteur pipette. The efrruginea stem-bark extract of Bridelia ferruginea was found to cause a non-significant increase in the weight of harvested organs of rats liver, heart and kidneys. These results further validate the use of B. Table 7 shows the effects of aqueous stem ferrufinea extract of Bridelia ferruginea on liver enzymes and renal functions.

Results were quoted as the radii mm of the zone of the inhibition around the well. Evaluations of acute toxicity of Momordica charantia extract using Wistar rats to determine safety levels and usefulness of the plant in Ethnochemotherapy. Their quantification as an index of oxidant stress status in vivo. Journal of Herbal Medicine.